The trail of Aron Keener had ended with him possessing Gordon Amherst's notes and a 3D biological printer. Obviously, his plans was to produce more of the virus.
Though, I think Jessica Kandel was well on the way towards a vaccine. I'm not sure if it is even remotely feasible for an amateur to produce a new strain unless we are following Hollywood rules of evil geniuses. In which case.. well, certainly!
So, what would be the new release of a virus?
The finale seasonal DLC is called the Last Stand. Let's start by asking who's last stand it shall be. If it is the opposition, then it would sound like Keener. He has betrayed the other antagonists, Amherst and Bliss. The cleaners and Rikers are only mobs at this point in the story. A new leader could emerge, however I don't think the title of Last Stand would suit them. So, I say Keener.
The other angle is that the Last Stand refers to the second division. That the choas and descent into the anarchy of betrayal has led us to fight for our own"Survival", not just New York, as we are hunted down by hardcore first wave bounty hunters and then a new nemesis , forcing us into a last stand. One we presumably will over come.
Obviously we will face Keener again. Will we confront him in his last stand, or will be simply fighting our own battle? Which would lead us into facing off Keener in Division 2.0.
The 3D printer is a strong plot device for expanding the story to new areas with the outbreak of a new virus. And in practical terms , we get to expand beyond our well jogged confines of Manhattan. After all, just using the virus without expanding would be a waste of story-line in Keener 's evil plans.
In the last two expansions, Conflict and Understand, we hadn't had new areas. Barring Incursions, which is only very small theaters. So, if we don't see a vast new area in Survival, I'd say we shouldn't be expecting any until Division 2.0.
And since Keener is in possession of the 3D printer, then he should still be our story line antagonist going into Division 2.0. Plus if he lacks the scientific proficiency to produce a new lethal strain of the virus, he will need another pawn (in a white lab coat) to assist in his evil plans. At this point, the story-line showed him slinking off alone into the shadows, leaving all of the story's minor antagonists dead in his wake. So, there needs to be more story-line, to work in new characters. I.e. new content, and Division 2.0.
Of course, whether the expansion is just new areas of New York, or a new city all together is another question. A new city would have more scope for a new story-line and a fresh start of the game. Expanding New York would mean just expanding the game. Less story-line, less new content. Which would Massive prefer with the future of the game? A Big fresh continuance, or something more manageable, since the game's prospects have tank recently.
So, Last Stand doesn't look like the Last Stand will be Keener's finale. Maybe a counter assault from his first waves as he prepares new conspirators in another city for the release of the new virus.
That's my stab at it. Not perfect. Not conclusive. What's other people's thoughts?
edit: antagonist, antagonist, antagonist...